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Why is Polaramine prescribed?

Polaramine (Dexchlorpheniramine) is an antihistamine which is prescribed to treat allergic reactions and symptoms of allergies, such as runny nose, sneezing, itchy eyes, and skin reactions. The medication is also used for seasonal and perennial allergic rhinitis, allergic conjunctivitis, urticaria (hives), and mild allergic skin conditions. In some cases, it may be prescribed to reduce allergic reactions to blood or plasma transfusions.

What does it do?

Polaramine (Dexchlorpheniramine) works by blocking histamine, a chemical in the body responsible for allergy symptoms like itching, swelling, and congestion. It competes with histamine for H1-receptor sites in the gastrointestinal tract, blood vessels, and respiratory system, preventing allergic reactions.

How should I take it?

Polaramine (Dexchlorpheniramine) is typically taken by mouth once a day every 6 hours and may be reduced to as needed. It’s best to take Polaramine with or without food, but avoid alcohol and other sedatives, as they can increase drowsiness.

What if I missed a dose?

If you miss a dose of Polaramine, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take double or extra doses to make up for the missed one.

What are the special precautions before taking Polaramine?

Inform your doctor about all the medications you are taking, your current and previous medical history.

Before taking Polaramine, here are several important precautions to keep in mind:

• Do not take Polaramine if you are allergic to Dexchlorpheniramine or any of the ingredients in the medication.
• Combining Polaramine with alcohol, tranquilizers, or other sedatives can intensify drowsiness and dizziness.
• Discuss your medical history with your doctor, particularly if you have glaucoma, asthma, enlarged prostate, hypertension, or stomach ulcer or a history of immune system disorders, as antihistamines may worsen these conditions.
• This medication can cause drowsiness, so avoid activities requiring mental alertness, such as driving or operating machinery.
• Individuals aged 60 and older, as well as those under 18, may have a higher likelihood of experiencing certain side effects from dexchlorpheniramine. Consult your healthcare provider to assess your risks and determine the safest course of treatment.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Drowsiness or tiredness
• Dizziness or feeling off balance
• Dry mouth, nose, or throat
• Nausea or vomiting

Serious side effects may include:
• Difficulty urinating or inability to empty the bladder
• Severe drowsiness or confusion
• Seizures
• Irregular heartbeat
• Swelling of the face, lips, mouth, tongue, or throat

This is not a complete list of all possible side effects, and others may occur. For more information about side effects, please consult your healthcare provider.

Is it safe to take it with another drug?

Polaramine (Dexchlorpheniramine) can interact with various medications, so it's important to check for potential interactions before taking it with another drug. Make sure to discuss with your doctor if you have taken a monoamine oxidase inhibitor (MAOI) in the past two weeks, as these are used for depression or Parkinson’s disease.

Also, disclose any medications that cause dizziness or drowsiness, including pain relievers, allergy medicines, sleep aids, or anxiety treatments.

• Codeine
• Morphine
• Dextropropoxyphene
• Warfarin

This doesn't cover all the potential drug interactions, always consult your doctor or pharmacist before combining Polaramine with other medications to ensure safety.

How should I store it?

Polaramine should be stored in its original container at room temperature, ideally between 20°C and 25°C (68°F and 77°F).

What action should I take in case of overdose?

If you suspect an overdose of Polaramine (Dexchlorpheniramine), it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Symptoms of overdose may include severe drowsiness, confusion, hallucinations, difficulty breathing, or seizures.

Is it safe for pregnant or breastfeeding women?

Polaramine (Dexchlorpheniramine) is not recommended for pregnant or breastfeeding women unless prescribed by a doctor. While it is sometimes used during pregnancy, it should be taken with caution, especially in the first trimester, as antihistamines may affect fetal development.

For breastfeeding, Polaramine can pass into breast milk and may cause drowsiness or irritability in the infant. If needed, a healthcare provider may suggest alternative antihistamines that are safer during pregnancy and lactation.

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