Why is Pradaxa prescribed?

Dabigatran (Pradaxa) is prescribed for patients with systemic embolism and/or deep vein thrombosis and is also used to prevent them from occurring if patients had undergone hip replacement surgery. Pradaxa is also indicated to minimize the risk of stroke and systemic embolism in patients suffering from irregular heartbeats known as atrial fibrillation.

What does it do?

Patients suffering from deep vein thrombosis, pulmonary embolism and atrial fibrillation have one thing in common – blood clots. They have higher chances of developing clots or in fact, they already have them. Dabigatran, a direct thrombin inhibitor, works by inhibiting the formation of thrombin which in turn, decreases blood clot formation to prevent and treat these conditions.

How should I take it?

Pradaxa and its generic equivalents are currently available in 75mg, 110mg, and 150mg tablets. Each tablet should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Pardaxa?

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you have stomach ulcers, kidney, heart and blood problems, and if you have any allergies to Dabigatran or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Pradaxa, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Headache
• Diarrhea
• Nausea
• Stomach upset
• Heartburn

Serious side effects may include:
• Frequent gum and nose bleeding
• Chest pain or tightness
• Reddish, pinkish or brownish urine
• Unusual bruising
• Heavy menstruation
• Rashes
• Difficulty of breathing
• Wheezing

Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Pradaxa with any of the following medications:

• Advil
• Aspirin
• Carvedilol
• Celebrex
• Clexane
• Clopidogrel
• Cordarone
• Coreg
• Effient
• Heparin
• Ibuprofen
• Ketoconazole
• Lovenox
• Naproxen
• Omeprazole
• Plavix
• Rifampin
• Simvastatin
• Warfarin
• Xarelto

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Pradaxa in a tight container in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Data regarding the use of Pradaxa in pregnant women are not enough to determine any congenital abnormalities or miscarriages during their pregnancy. However, it is important to consider that the risk of bleeding during pregnancy and delivery is relatively high.

At present, there is limited information regarding the presence of Dabigatran in milk or its effects in breastfed infants. Nevertheless, breastfeeding is not recommended during treatment.

Inform your doctor if you are pregnant or breastfeeding or planning on doing so to ensure that the benefits of taking the medication outweigh the risks.

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