Why is Pristiq ER prescribed?

Pristiq ER, with generic name Desvenlafaxine, is used to manage symptoms of depression. Depression is a mood disorder that affects the behavior and way of thinking of an individual causing a persistent loss of interest and sadness that affects daily functioning.

What does it do?

Desvenlafaxine is classified as a selective serotonin and norepinephrine reuptake inhibitor, which increases the levels of certain substances (serotonin and norepinephrine), that regulate mood and mental balance.

How should I take it?

Pristiq ER is currently available as 50mg and 100mg extended-release tablets taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Pristiq ER?

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Pristiq, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Pristiq, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Changes in bowel movement
• Appetite changes
• Fatigue
• Dizziness
• Dry mouth
• Drowsiness
• Sweating
• Enlarged pupils (the black circle in the center of the eye)
• Changes in libido
• Pain, burning or tingling in any part of the body
• Difficulty in urination

Serious side effects include:
• Itching, hives, or rash
• Swelling of any part of the face
• Hoarseness
• Difficulty breathing or swallowing
• Rapid or irregular heartbeat
• Hallucinations
• Seizures
• Unusual bleeding
• Easy bruising
• Red or purple dots on the skin
• Nausea
• Vomiting
• Memory problems
• Loss of focus
• Weakness
• Incoordination
• Loss of consciousness

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Pristiq with any of the following medications:

• Abilify
• Adderall
• Amitriptyline
• Ativan
• Azilect
• Celexa
• Clonazepam
• Effexor
• Gabapentin
• Granisetron
• Ibuprofen
• Lexapro
• Lithium
• Lyrica
• Meperidine
• Mirtazapine
• Neurontin
• Phentermine
• Prozac
• Ondansetron
• Ozanimod
• Remeron
• Rexulti
• Seroquel
• St. John’s wort
• Topamax
• Tramadol
• Trazodone
• Vyvanse
• Wellbutrin
• Wellbutrin XL
• Xanax
• Zolmitriptan

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Pristiq ER in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Desvenlafaxine is not recommended for use in pregnant women, women trying to get pregnant, or are breastfeeding, and should only be used if the benefits outweigh the risks associated with the use of this medication. Hence, the potential risks and benefits of using Pristiq ER in pregnant or breastfeeding infants should be carefully considered.

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