Why is Rectiv prescribed?

Nitroglycerin (Rectiv) ointment is prescribed for the treatment of pain due to chronic anal fissure. It usually occurs in infants and is associated with pain and bleeding when passing stool.

What does it do?

An anal fissure is a tear or cut in the lining of the anus that causes pain. It may be caused by constipation, passing stools that are hard or large, diarrhea, anal intercourse, or childbirth. Rectiv belongs to a drug class called vasodilators and it causes dilation of the blood vessels to decrease pain and pressure.

How should I apply it?

Rectiv and its generic equivalents are currently available as a 0.4% ointment. It should only be applied around the anal canal or the outside of the anus.

Use a finger covering such as disposable gloves, a finger cot, or plastic-wrap to apply the ointment and throw it away after use.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if used properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, apply it immediately and adjust the time of your next dose depending on your doctor’s advice. Never apply two doses at the same time just to make up for your missed dose.

What are the special precautions before applying Rectiv?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Rectiv or any other ingredients included in the manufacture of this medication.

Rectiv may cause drowsiness. Limit alcohol intake and avoid doing activities that require your full attention such as driving or operating machinery until you feel it is safe to do so.

Rectiv may cause severe headaches when you apply it. Consult your doctor on how to manage your headaches.

For the drug label information of Rectiv, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Dizziness
• Flushing
• Headache
• Irritation of the treatment site
• Redness of the treatment site

Serious side effects include:
• Chest pain
• Difficulty breathing
• Fainting
• Lightheadedness
• Rashes
• Slow heartbeat

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Rectiv with any of the following medications:

• Aldesleukin
• Altace
• Anafranil
• Avanafil
• Baclofen
• Bepridil
• Bromocriptine
• Buprenorphine
• Butabarbital
• Cafergot
• Captopril
• Cariprazine
• Chlordiazepoxide
• Cialis
• Dapsone
• Desyrel
• Diazepam
• Dostinex
• Elavil
• Emla
• Enalapril
• Fosinopril
• Guanfacine
• Hydrocodone
• Hydroxyzine
• Iloprost
• Isocarboxazid
• Levitra
• Linezolid
• Loxitane
• Methylergonovine
• Nalbuphine
• Nimodipine
• Norvasc
• Orphenadrine
• Pentazocine
• Plendil
• Promethazine
• Propoxyphene
• Quazepam
• Riociguat
• Selegiline
• Silenor
• Sodium nitrite
• Trimipramine
• Univasc
• Viagra
• Zaleplon
• Zanaflex

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Rectiv in its container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Rectiv in pregnant women has not established its developmental risks.

There is also limited data on the presence of Rectiv in human milk or its effects on the breastfed infant.

The use of Nitroglycerin in pregnant and breastfeeding women should be carefully evaluated to determine if its potential benefits outweigh the risks.

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