Why is Relafen prescribed?

Nabumetone (Relafen) is being prescribed in combination with other drugs for the management of arthritis, gout and bursa sac that causes pain, swelling, inflammation, and stiffness of the joint muscles.

What does it do?

Nabumetone, classified under Non-steroidal Anti-inflammatory Drugs (NSAIDs), produces properties such as analgesic and anti-inflammatory effects that primarily works by inhibiting the enzyme called Prostaglandin that is responsible for pain sensation and inflammation; thus, reduce swelling and pain.

How should I take it?

Relafen is currently available as a 500mg tablet. Each tablet should be taken as a whole (do not split) by mouth, with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Relafen?

Before taking Nabumetone, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history especially if you have or have had bleeding problems, clotting problems, heart disease, nasal polyps, liver disease, stroke, intestinal problems and kidney disease.

Avoid drinking alcohol as this may cause dizziness or drowsiness which can add to the effects of Nabumetone.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Relafen, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Abdominal pain
• Constipation
• Diarrhea
• Dizziness
• Drowsiness
• Headache
• Increased blood pressure
• Itching
• Heartburn
• Nausea
• Sweating

Serious side effects include:
• Black stool
• Bone marrow depression
• Chest pain
• Coughing of blood
• Dark urine
• Dysphagia
• Dyspnea
• Hallucinations
• Leukopenia
• Numbness
• Ringing of ears
• Slurred speech
• Yellowing of eyes and skin

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Relafen with any of the following medications:

• Aleve
• Aldosterone
• Alfalfa
• Allopurinol
• Aliskiren
• Arthrotec
• Aspirin
• Betrixaban
• Captopril
• Celebrex
• Coumadin
• Diovan
• Enoxaparin
• Flector
• Fosinopril
• Furosemide
• Indocin
• Jantoven
• Ketorolac
• Lasix
• Lifezar
• Losartan
• Mobic
• Naproxen
• Pennsaid
• Pradaxa
• Symmetrel
• Tacrolimus
• Zestril

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Relafen at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Nabumetone to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes. In addition, during 30 weeks of gestation (third trimester), Indomethacin may increase the risk for developing fetal ductus arteriosus.

Limited data have been established indicating the presence of Nabumetone in human milk. Consult your doctor first before breastfeeding.

The use of Nabumetone in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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