Why is Spiriva prescribed?

Spiriva is indicated in the maintenance treatment of patients with bronchospasms caused by Chronic Obstructive Pulmonary Disease (COPD) and is also used to minimize the worsening of its symptoms.

Tiotropium bromide is the generic name of Spiriva and is available as Spiriva Handihaler and Spiriva Respimat. Spiriva Respimat is the only form indicated for asthma in children over 6 years old, but it is not indicated in the relief of acute bronchospasms.

What does it do?

COPD patients experience symptoms such as difficulty breathing, wheezing, shortness of breath caused by bronchitis, or emphysema or both. Tiotropium belongs to a drug class called bronchodilators that help in the relaxation of the lung muscles which increases the flow of air into the lungs thereby alleviating the patient’s symptoms.

How should I use it?

Spiriva is currently available in two forms:

Spiriva Respimat 1.25mcg/actuation and 2.5mcg/actuation that is supplied with a cartridge and an inhaler. Do not use the Spiriva Respimat inhaler to administer other drugs.

Spiriva Handihaler 18mcg capsule together with a handihaler (device used to aid in the inhalation of the contents of the capsule). Only remove the capsules from the blister pack when it is time to use this medication. Do not swallow the capsules.

Both preparations, when prescribed, should be taken preferably at the same time every day or as instructed. The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if used properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, use it immediately and adjust the time of your next dose depending on your doctor’s advice. Never administer two doses at the same time just to make up for your missed dose.

What are the special precautions before using Spiriva?

Inform your doctor about all the medications you are taking, your current and previous medical history especially if you have glaucoma, prostate enlargement, kidney and heart problems and any allergic reactions to Tiotropium, Ipatropium, Atropine or any other ingredients included in the manufacture of this medication.

Take caution when administering the medication to prevent the powders from reaching your eyes.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Spiriva Respimat, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Nausea
• Sneezing
• Vomiting
• Constipation
• Indigestion
• Runny nose
• White patches in the mouth

Serious side effects may include:
• Rashes or hives
• Shortness of breath or difficulty breathing
• Painful or difficulty urinating
• Irregular heartbeat
• Pain in the eyes
• Blurred vision

Is it safe to use it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered t. Immediately inform your doctor if you are taking Spiriva with any of the following medications:

• Advair Diskus
• Advair HFA
• Aminophylline
• Atropine
• Atrovent
• Avelox
• Benadryl
• Betapase
• Cisapride
• Combivent
• Cordarone
• Disopyramide
• Fluticasone
• Entocort
• Erythromycin
• Ipatropium bromide
• Pulmicort
• Quinidine
• Theobromine
• Theophylline
• Uniphyllin

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

The capsules should not be stored inside the handihaler. If the respimat inhaler has been used for 3 months or if the locking mechanism has been compromised, discard it properly.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Developmental risks associated with the use of Tiotropium in pregnant women have not been established.

Currently, there is also limited data on the presence of Tiotropium in human milk or its effects on the breastfed infant. The potential risks and benefits of using Spiriva in pregnant or breastfeeding infants should be carefully considered.

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