Why is Sporanox prescribed?

Itraconazole (Sporanox) is prescribed for the treatment of fungal infections that can cause skin problems such as rashes, bumps and itching.

What does it do?

Itraconazole, classified as an anti-fungal medication, primarily works by blocking the synthesis of ergosterol, which is an important part of the fungal membrane; thus, stopping the growth of fungus that can cause infection in the body.

How should I take it?

Sporanox is available as a 100mg capsule,intended for oral administration as a whole, not to be crushed or chewed, and should be taken with food as directed by the doctor.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is strictly advised that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Do not take two doses just to make up for your missed dose.

What are the special precautions before using Sporanox?

Before taking Itraconazole, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history, especially if you have or have had heart problems, seizures, cystic fibrosis, weakened immune system, liver disease, kidney disease, coronary artery disease, heart-valve disease and lung disease.

Avoid drinking alcohol as this may cause dizziness or drowsiness and can add to the effects of Itraconazole.

Consult your doctor regarding all the other medications you use before getting a surgery.

For the drug label information of Sporanox, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Dizziness
• Drowsiness
• Erectile dysfunction
• Fatigue
• Fever
• Headache
• Impotence
• Increased blood pressure
• Joint pain
• Loss of hair
• Muscle pain
• Nausea
• Swelling 
• Upset stomach

Serious side effects include:
• Blurred vision
• Clay-colored stool
• Dark urine
• Depression
• Dyspnea
• Dysrhythmia
• Jaundice
• Loss of appetite
• Loss of bladder control
• Renal impairment
• Tachycardia

Is it safe to use it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Sporanox with any of the following medications:

• Alfuzosin
• Aliskiren
• Avanafil
• Biaxin
• Budesonide
• Bromocriptine
• Carbatrol
• Clozapine
• Colchicine
• Conivaptan
• Coralan
• Cordarone
• Dexilant
• Diflucan
• Disopyramide
• Dormicum
• Dronedarone
• Eplerenone
• H2-bloc
• Imipramine
• Irinotecan
• Isoket
• Isordil
• Lipitor
• Lozol
• Mevacor
• Nexium
• Nisoldipine
• Pantoloc
• Plendil
• Quinidine
• Ranolazine
• Vabradine
• Xanor
• Zocor

If you are using any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Sporanox in room temperature(25°C) in a clean environment away from light and moisture.Do not refrigerate. Keep away from children. Do not remove the desiccant in the original container. Do not open the capsule. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Itraconazole to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.However, as per US FDA, Itraconazole is categorized as Pregnancy Category C which states that no potential harm and well-controlled studies have been done in humans; but animal studies have shown adverse effects on the fetus.

Limited data have been established indicating the presence of Itraconazole in human milk. Consult your doctor first before breastfeeding.

The use of Itraconazole in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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