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Why is Tarceva prescribed?

Tarceva (Erlotinib) is a chemotherapy medication used to treat non-small cell lung cancer (NSCLC) and pancreatic cancer.

What does it do?

Tarceva (Erlotinib) is a tyrosine kinase inhibitor that prevents certain proteins from attaching to the epidermal growth factor receptor (EGFR) on cells. EGFR is present on both healthy and cancerous cells and plays a key role in cell growth. Cancer cells typically have more EGFR proteins than normal cells. By blocking EGFR, Tarceva inhibits the growth and spread of cancer cells.

How should I take it?

Take this medication orally on an empty stomach, either at least 1 hour before or 2 hours after a meal, as prescribed by your doctor, typically once daily.

Avoid consuming grapefruit or drinking grapefruit juice while using this medication as it increases the risk of side effects, unless your doctor or pharmacist advises that it is safe.

What if I missed a dose?

Take the medicine on an empty stomach as soon as you remember, but if it's nearly time for your next dose, skip the missed dose. Do not take two doses at once.

What are the special precautions before taking Tarceva?

You should not take Tarceva if you are allergic to erlotinib and to ensure Tarceva is safe for you, inform your doctor if you have a history of:

• Dehydration
• Eye problems
• Lung or breathing issues (other than lung cancer)
• Kidney disease
• Liver disease
• Stomach bleeding
• Smoking
Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions.
Common side effects may include:
• Acne
• Diarrhea
• Dry skin
• Itching
• Loss of appetite
• Mouth sores
• Nausea and vomiting
• Weakness or fatigue
• Weight loss
Serious side effects may include:
• Allergic reactions such as skin rash, itching or hives, swelling of the face, lips, or tongue
• Breathing difficulties
• Cough
• Eye irritation or pain
• Fever
• Redness, blistering, peeling, or loosening of the skin, including inside the mouth
• Signs of bleeding
• Signs of kidney injury
• Signs of liver damage
• Signs of a stroke
This list may not cover all possible side effects. Contact your doctor for medical advice regarding any side effects.
Is it safe to take it with another drug?

Tarceva (Erlotinib) may interact with certain medications or supplements. Always inform your doctor and pharmacist about any other medications or supplements you are currently taking.

Using Tarceva with any of the following medications is generally not recommended, although it may be necessary in some cases. If both medications are prescribed together, your doctor may adjust the dosage or frequency of one or both medications.

• Acenocoumarol
• Amiodarone
• Boceprevir
• Carbamazepine
• Cimetidine
• Ciprofloxacin
• Clarithromycin
• Cobicistat
• Conivaptan
• Dexlansoprazole
• Enzalutamide
• Esomeprazole
• Famotidine
• Nelfinavir
• Nizatidine
• Omeprazole
• Pantoprazole
• Rifabutin
• Rifampin
• Rifapentine
• Ritonavir
• Saquinavir
• St. John's Wort
• Telaprevir
• Telithromycin
• Voriconazole
• Warfarin
The list includes some medications that may interact with Erlotinib, but this is not a complete list of all possible interactions.
How should I store it?
Store at room temperature, away from light and moisture. Keep all medications out of reach of children.
What action should I take in case of overdose?
If someone has overdosed and is experiencing severe symptoms such as fainting or difficulty breathing, call emergency services immediately.
Is it safe for pregnant or breastfeeding women?
Tarceva is not recommended during pregnancy, as it may harm the fetus or cause a miscarriage. It is unclear whether this drug passes into breast milk, so breastfeeding while using Tarceva is not advised.
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