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Why is Tarka prescribed?

Tarka (Verapamil HCl/Trandolapril) is prescribed to treat high blood pressure (hypertension). By lowering blood pressure, it helps reduce the risk of stroke, heart attack, and kidney problems.

What does it do?

Tarka is a combination medication that includes trandolapril, an ACE inhibitor that relaxes blood vessels by blocking a substance that causes them to tighten, and verapamil, a calcium channel blocker that helps blood vessels relax while also slowing the heart rate. Together, these components enhance blood flow, reduce the heart’s workload, and effectively lower blood pressure.

How should I take it?

Take Tarka exactly as prescribed by your doctor. Take Tarka once daily with food, swallowing the extended-release tablet whole without crushing or chewing. For best results, take it at the same time each day to maintain steady blood levels.

What if I missed a dose?

If you miss a dose of Tarka, take it as soon as you remember. However, if your next scheduled dose is approaching, skip the missed dose and proceed with your usual dosing routine. Do not take extra or double doses to make up for the missed dose.

What are the special precautions before taking Tarka?

Inform your doctor about all the medications you are taking, your current and previous medical history. Before taking Tarka, here are several important precautions to keep in mind:

Disclose all your current or past medical conditions to your doctor, particularly if you have:

• Angioedema
• Heart conditions like AV block or sick sinus syndrome
• Kidney or liver problems
• Liver problems
• Sever heart failure
• Diabetes
• Low blood pressure (Hypotension
• Systemic lupus erythematosus

If you are pregnant, considering pregnancy, or breastfeeding, consult your doctor to understand the potential risks and benefits of taking this medication.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Dizziness or lightheaded
• Dry cough
• Constipation
• Headache
• Fatigue

Serious side effects may include:
• Low blood pressure (Hypotension)
• Irregular or slow heart rate
• Swelling of the face, lips or throat
• Difficulty breathing
• Yellowing of the skin or eyes (jaundice)

This is not a complete list of potential side effects, and additional reactions may occur. For detailed information and medical guidance, consult your healthcare provider.

Is it safe to take it with another drug?

Tarka (Verapamil Hcl/Trandolapril) can interact with various medications, so it's important to check for potential interactions before taking it with another drug. Some interactions may increase side effects or reduce effectiveness.

Before taking Tarka, consult your doctor if you are using any of the following medications:

• Beta-blockers
• Statins
• Lithium
• Diuretics and NSAID (nonsteroidal anti-inflammatory drugs)
• Antidepressants
• Other blood pressure medications

This is not a complete list of all the potential drug interactions, always consult your doctor or pharmacist before combining Tarka with other medications to ensure safety.

How should I store it?

Tarka should be stored in its original container at room temperature, ideally between 15°C and 25°C (59°F to 77°F). Keep the medication in a cool, dry place, away from direct sunlight, and ensure it is kept out of reach of children and pets.

What action should I take in case of overdose?

If you suspect an overdose of Tarka (Verapamil Hcl/Trandolapril), it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Overdose symptoms may include severe dizziness, slow or irregular heartbeat, low blood pressure, muscle weakness, or chest pain.

Is it safe for pregnant or breastfeeding women?

Tarka (Verapamil HCl/Trandolapril) is not considered safe during pregnancy or breastfeeding. Tarka is classified as Pregnancy Category D, indicating positive fetal risk based on human data. Trandolapril (ACE inhibitor) may cause serious harm or even death to a developing baby, especially in the second and third trimesters, while verapamil could interfere with uterine contractions if used late in pregnancy. As a result, most guidelines recommend avoiding Tarka during pregnancy unless no safer alternatives are available and the benefits outweigh the risks.

Regarding breastfeeding, verapamil may pass into breast milk, though usually in small amounts, while the presence of trandolapril in human milk is unknown, though detected in animal milk. Because of the risk of significant side effects in nursing infants, Tarka is typically not advised for use during breastfeeding. If you are pregnant, considering pregnancy, or breastfeeding, speak with your doctor about safer options.

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