Why is Topamax prescribed?

Topamax, with the generic name Topiramate, is used to manage and control several types of seizures like tonic-clonic seizures, partial seizures, and seizures secondary to Lennox-Gastaut syndrome. Tonic-clonic seizures are also known as grand mal seizures which involve the whole body and are often associated with loss of awareness. In contrast to partial seizures which only affects one part of the brain and does not affect awareness. Topamax can also be prescribed to prevent migraine headaches, however, cannot provide relief of ongoing headaches.

What does it do?

Topiramate belongs to a class of medications called anticonvulsants that regulate the brain’s electrical activity to decrease abnormal excitation and prevent seizures.

How should I use it?

Topamax is currently available as 25mg, 50mg, 100mg, and 200mg tablets taken whole (not split, chewed, or crushed) by mouth with or without food. Topamax is also available as 15mg and 25mg sprinkle capsules poured over soft food and taken by mouth.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The proper use of medications is needed to achieve the desired effect of any drug. As much as possible, strictly follow your doctor’s prescribed dosing schedule. If you miss a dose, take it immediately. However, if it’s close to the next scheduled dose, skip the missed dose and proceed with the regular dosing schedule. Never take two doses at the same time to make up for a missed dose, unless told otherwise.

What are the special precautions before using Topamax?

Topamax can cause dizziness or drowsiness. Avoid driving or operating heavy machinery while taking this medication. Avoid the intake of alcohol as this can exacerbate dizziness and drowsiness associated with the intake of this medication.

Topamax can increase your risk of developing kidney stones. Take plenty of water (about 8 glasses a day) to prevent the formation of kidney stones.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Topamax, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Topamax tablets and Topamax sprinkle capsules, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Anxiety
• Headache
• Drowsiness
• Dizziness
• Uncontrollable shaking
• Weight loss
• Changes in bowel movement
• Dry mouth
• Nosebleed
• Muscle pain
• Heavy menstrual bleeding
• Unusual bleeding
• Easy bruising

Serious side effects include:
• Itching, hives, or rash
• Muscle pain or weakness
• Chest pain
• Rapid and irregular heartbeat
• Swelling, redness, or pain in the eyes
• Flu-like symptoms
• Worsening seizures
• Changes in vision (blurring, double vision, eye pain)
• Difficulty in concentration
• Memory problems
• Cognitive problems
• Confusion

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Topamax with any of the following medications:

• Abilify
• Atropine
• Azatadine
• Benadryl
• Brexpiprazole
• Celexa
• Clozapine
• Cymbalta
• Doxepin
• Doxepin topical
• Flexeril
• Geodon
• Glucophage
• Glycopyrrolate
• Haloperidol
• Imipramine
• Lexapro
• Lyrica
• Meclizine
• Metaglip
• Methadone
• Neurontin
• Olanzapine
• Oxycodone
• Percocet
• Phentermine
• Prozac
• Risperdal
• Seroquel
• Tramadol
• Trazodone
• Vesicare
• Xanax
• Zoloft
• Zonegran

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Keep Topamax in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Topamax is acceptable for use in pregnant women, women trying to get pregnant, or are breastfeeding only if the benefits outweigh the risks associated with its use. Consider both the developmental and health benefits of breastfeeding, along with the mother’s clinical need for this medication.

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