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Why is Tribenzor prescribed?

Tribenzor (Olmesartan/Amlodipine/HCTZ)Tribenzor is prescribed to treat high blood pressure (hypertension) in adults. It's typically used when blood pressure is not adequately controlled by one or two medications alone.

What does it do?

Tribenzor combines three active ingredients, each with a distinct mechanism:

• Olmesartan: An angiotensin II receptor blocker (ARB) that works by inhibiting the tightening of blood vessels, helping them stay relaxed and open to lower blood pressure.
• Amlodipine: A calcium channel blocker that relaxes blood vessels and improves blood flow.
• Hydrochlorothiazide (HCTZ): A thiazide diuretic that helps the body eliminate excess salt and water, reducing fluid volume.

Together, these actions result in lower blood pressure through complementary pathways.

How should I take it?

Always follow your doctor’s instructions or the directions on the product label when taking this medication. Tribenzor (Olmesartan/Amlodipine/HCTZ) is typically taken once daily by mouth with or without food, with the exact starting dose based on your prior blood pressure treatment.

Your healthcare provider may adjust your dosage after two weeks depending on how well you respond. The maximum recommended dose is 40 mg/10 mg/25 mg once daily, and it’s important to follow your provider’s instructions closely for optimal blood pressure control and safety.

What if I missed a dose?

If you miss a dose of Tribenzor, take it as soon as you remember. However, if your next scheduled dose is approaching, skip the missed dose and proceed with your usual dosing routine. Do not take extra or double doses to make up for the missed dose.

What are the special precautions before taking Tribenzor?

Always inform your doctor about all the medications you are taking, your current and previous medical history.

Do not take Tribenzor if you're allergic to Olmesartan, Amlodipine, Hydrochlorothiazide, or any of the ingredients in the medication.

Disclose all your current or past medical conditions to your doctor, particularly if you have:

• Diabetes
• Heart problems
• Kidney problems
• Liver problems
• Electrolyte imbalances
• Eye problems
• Glaucoma or eye disorders
• Gout or lupus

Tribenzor can affect your ability to stay alert or coordinate movements, so it's best to avoid driving or operating machinery until you’re confident about how your body responds to the medication.

If you are pregnant, considering pregnancy, or breastfeeding, consult your doctor to understand the potential risks and benefits of taking this medication.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Diarrhea
• Dizziness
• Nausea
• Headache
• Fatigue

Serious side effects may include:
• Glaucoma
• Severe hypotension
• Heart attack or worsening angina
• Severe or persistent diarrhea

This is not a complete list of potential side effects, and additional reactions may occur. For detailed information and medical guidance, consult your healthcare provider.

Is it safe to take it with another drug?

Tribenzor (Olmesartan/Amlodipine/ HCTZ) can interact with various medications, so it's important to check for potential interactions before taking it with another drug. Some interactions may increase side effects or reduce effectiveness.

Before taking Tribenzor, consult your doctor if you are using any of the following medications:

• Corticosteroids
• Lithium
• Insulin
• Diuretic
• Potassium supplements or salt substitutes
• Other blood pressure medications

This is not a complete list of all the potential drug interactions, always consult your doctor or pharmacist before combining Tribenzor with other medications to ensure safety.

How should I store it?

Tribenzor should be kept in its original container and stored at room temperature, ideally between 20°C and 25°C (68°F to 77°F), to maintain its effectiveness.

What action should I take in case of overdose?

If you suspect an overdose of Tribenzor (Olmesartan/Amlodipine/ HCTZ), it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Overdose symptoms may include severe dizziness or fainting due to low blood pressure, irregular heartbeat, muscle weakness or cramps, or reduced urination.

Is it safe for pregnant or breastfeeding women?

Tribenzor is not considered safe for pregnant women due to its potential to harm fetal development, especially from olmesartan, which may cause kidney dysfunction and fetal injury, and hydrochlorothiazide, which poses additional neonatal risks.

Likewise, it is not recommended during breastfeeding because its components can pass into breast milk and may disrupt electrolyte balance or reduce milk production, making alternative treatments or feeding options advisable under medical guidance.

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