Why is Uniphyl prescribed?

Theophylline, with brand name Uniphyl, is used to prevent and treat symptoms of asthma and chronic obstructive disease (COPD; chronic bronchitis, and emphysema) like chest tightness, shortness of breath, and wheezing.

What does it do?

Theophylline is classified under methylxanthines, which facilitates the relaxation and opening of the airways in the lungs to relieve and prevent symptoms mentioned above.

How should I take it?

Uniphyl is currently available as a 200mg, 300mg, and 400mg extended-release tablets (Theophylline ER) taken whole (not split, chewed, or crushed), by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Uniphyl?

Avoid the intake of caffeinated food or beverages like coffee, tea, cocoa, and chocolate as these could increase the side effects associated with the intake of theophylline.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Theophylline ER or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Theophylline, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Abdominal pain
• Diarrhea
• Headache
• Restlessness
• Sleep disturbance
• Irritability

Serious side effects may include:
• Rash
• Rapid and irregular heartbeat
• Seizures
• Vomiting

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Uniphyl with any of the following medications:

• Advair Diskus
• Atenolol
• Azithromycin
• Betaxolol
• Bisoprolol
• Caffeine
• Carvedilol
• Cimetidine
• Cipro
• Combigan eye drops
• Combivent
• Cordarone
• Deferasirox
• Duoneb
• Ephedrine
• Enoxacin
• Erythromycin
• Esmolol
• Interferon alfa
• Interferon-beta
• Iohexol
• Iopamidol
• Isoptin
• Labetalol
• Labetalol
• Nadolol
• Nexium
• Nizoral
• Prednisone
• Proair HFA
• Prograf
• Rapamune
• Sotalol
• Sporanox
• St. John’s wort
• Symbicort
• Tramadol
• Ventolin HFA
• Vfend
• Xanax
• Zafirlukast
• Zileuton
• Zyrtec

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Uniphyl in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There is still limited data regarding the use of Theophylline in pregnant women, women trying to get pregnant, and breastfeeding women. Hence, the potential risks and benefits of using Uniphyl in pregnant or breastfeeding infants should be carefully considered.

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