Why is Welchol prescribed?

Welchol, with generic name Colesevelam, is prescribed together with diet, exercise, and weight loss in people with elevated cholesterol levels. It is also used to treat children aged 10 to 17 years old diagnosed with familial heterozygous hypercholesterolemia. Familial heterozygous hypercholesterolemia is an inherited condition where there is a defect in the removal of cholesterol in the body. It can also be used to control blood sugar levels of people with type 2 diabetes.

What does it do?

Bile acids are formed upon cholesterol breakdown and removal of these bile acids aid in lowering cholesterol levels. Colesevelam, classified under bile acid sequestrants, binds bile acids in the intestines to limit their absorption, hence lowering cholesterol levels.

How should I take it?

Welchol is currently available as 625mg tablet taken whole (not split, chewed, or crushed) by mouth, with food. This medication only controls your condition and does not cure it. Take this medication regularly unless told otherwise by your doctor.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Welchol?

Avoid the intake of fatty or cholesterol-rich foods while taking Welchol. Follow the dietary and exercise recommendations discussed by your dietitian or doctor.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Welchol or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Welchol tablets, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Headache
• Vomiting
• Nausea
• Heartburn
• Abdominal pain
• Muscle pain
• Flatulence
• Constipation
• Fatigue

Serious side effects include:
• Itching, hives, and rash
• Swelling of any part of the face or limbs
• Severe abdominal pain
• Severe nausea or vomiting

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Welchol with any of the following medications:

• Aminophylline
• Bexarotene
• Calcifediol
• Calcitriol
• Cholecalciferol
• Combipatch
• Cortisone
• Cordarone
• Coumadin
• Deferasirox
• Ergocalciferol
• Flecainide
• Gemfibrozil
• Glimepiride
• Glucophage
• Hytone
• Lithium
• Loestrin
• Lopitamide
• Multivitamins
• Multivitamins with fluoride
• Multivitamins with iron
• Mycophenolate mofetil
• Mycophenolic acid
• Phenobarbital
• Plan B
• Premarin
• Prempro
• Prograf
• Pulmicort
• Rapamune
• Rhinocort
• Restasis
• Teriflunomide
• Venetoclax
• Vitamin A
• Vitamin E
• Vivelle dot

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Welchol in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Colesevelam is acceptable for use in pregnant women, women trying to get pregnant, and breastfeeding women. Hence, the potential risks and benefits of using Welchol in pregnant or breastfeeding infants should be carefully considered.

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