Why is Xarelto prescribed?

Xarelto, with generic name Rivaroxaban, is prescribed to prevent and treat blood clots. Blood clots can occur in the thigh or leg (deep vein thrombosis) or the lungs (pulmonary embolism). It is also useful in preventing stroke and blood clot formation on people diagnosed with atrial fibrillation (irregular and often rapid heartbeat) without heart valve disease. Xarelto can also be used along with other medications to decrease the risk of heart attacks or death in people with heart disease or those with poor blood circulation on the arms and legs.

What does it do?

Xarelto, under a drug class called factor Xa inhibitors, decreases the ability of the blood to form clots. This minimizes the risk of developing heart attacks, stroke and other conditions.

How should I take it?

Xarelto is currently available in 10mg, 15mg, and 20mg tablets. Each tablet should be taken as a whole with food. It can be crushed and mixed with apple sauce if there is difficulty in swallowing the drug. However, remember to finish the mixture right after preparing, and discard if not used within four hours. Xarelto can also be given through feeding tubes.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The proper intake of medications is needed to achieve the desired effect of any drug. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose, depending on your doctor’s advice. Never take two doses at the same time, unless told otherwise. Do not take two doses to make up for your missed dose.

What are the special precautions before taking Xarelto?

Inform your doctor about all the medications you are taking, your current and previous medical history such as bleeding disorders or autoimmune disorders, and any allergic reactions to Xarelto or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery (especially heart/valve replacement) or if you are planning to get one.

Inform your doctor immediately if you experience sudden heavy bleeding anywhere in the body that does not stop.

For the drug label information of Xarelto, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Serious side effects include:
• Bloody, black, or tar-like stools
• Pink or brown discoloration of urine
• Coughing up or vomiting blood/coffee ground material
• Frequent nosebleeds or bleeding from your gums
• Heavy menstrual bleeding
• Weakness/tiredness
• Headache
• Dizziness or fainting
• Blurred vision
• Pain in arm or leg
• Rash, itching, blisters, or peeling skin
• Difficulty breathing or swallowing
• Pain or swelling at wound sites

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Xarelto with any of the following medications:

• Acular
• Advil
• Aspirin
• Celebrex
• Coumadin
• Dilantin
• Eliquis
• Emend
• Erythromycin
• Lovenox
• Nizoral
• Phenobarbital
• Plavix
• Rifadin
• Sporanox
• Tegretol
• St. John’s wort
• Vfend

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Xarelto in its original container in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There is still limited data on the developmental risks associated with the use of Xarelto in pregnancy, its presence in human milk, or its effects on the breastfed infant. Hence, the potential risks and benefits of using Xarelto in pregnant or breastfeeding infants should be carefully considered.

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