Why is Xifaxan prescribed?

Xifaxan is prescribed to treat traveler’s diarrhea both in adults and children at least twelve years old. It can also be used to treat irritable bowel syndrome (with diarrhea) in adults.

What does it do?

Rifaximin is an antibiotic that works by stopping the growth of bacteria that causes diarrhea. Once the infection is cleared, the symptoms will also resolve.

How should I use it?

Xifaxan is currently available in 200mg or 550mg tablets, taken whole (not chewed or crushed), by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

Taking the dose properly at the scheduled time is needed to attain the desired effect of the drug. If you forgot to take your medicine, immediately take the next dose to make up for the missed dose. However, if it is near the time of the next dose, skip the missed dose and catch the next dose at the regular time. Never take two doses just to make up for your missed dose.

What are the special precautions before taking Xifaxan?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Xifaxan or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Xifaxan, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Dizziness
• Abdominal pain
• Nausea
• Headache
• Fatigue
• Joint pains

Serious side effects include:
• Persistent watery or bloody diarrhea with abdominal pain and fever during treatment or after 2 months
• Itching, hives, rash
• Difficulty of breathing or swallowing
• Swelling of any part of the face or limbs

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Xifaxan with any of the following medications:

• Anisindione
• Apalutamide
• Brigatinib
• Cabozantinib
• Capmatinib
• Coumadin
• Cholera Vaccine, Live
• Daclatasvir
• Dicumarol
• Elagolix
• Eliglustat
• Encorafenib
• Enzalutamide
• Erdafitinib
• Flibanserin
• Fostamatinib
• Fostemsavir
• Gemfibrozil
• Ibrutinib
• Istradefylline
• Lasmiditan
• Neratinib
• Nilotinib
• Ponatinib
• Rolapitant
• Sarecycline
• Sorafenib
• Teriflunomide
• Tucatinib
• Typhoid Vaccine, Live
• Ulipristal
• Venetoclax

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Xifaxan in its original packaging and store it in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There is still limited data on the developmental risks associated with the use of Xifaxan in pregnancy. It is advisable to stop breastfeeding when using this medication especially if nursing infant is less than one month old. Hence, the potential risks and benefits of using Xifaxan in pregnant or breastfeeding infants should be carefully considered.

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