Why is Zocor prescribed?

Zocor, with the generic name Simvastatin, is prescribed to reduce the risk for developing heart attack and stroke and decrease the need for surgical management in people diagnosed with heart disease or are at risk of developing such condition. It is also prescribed, together with diet, exercise, and weight-loss, to lower the levels of low-density lipoprotein/LDL (a.k.a. “bad” cholesterol) and increase the levels of high-density lipoprotein/HDL (a.k.a. “good” cholesterol) in the blood in adults. It is also prescribed to children ages 10-17 years of age who are diagnosed with familial heterozygous hypercholesterolemia, a genetic disorder of cholesterol metabolism.

What does it do?

Simvastatin belongs to a class of medications called HMG-COA reductase inhibitors that works by slowing the production of cholesterol in the body to prevent build up in the walls of arteries, heart, brain, and other parts of the body to reduce the risk of developing a heart attack and stroke.

How should I take it?

Zocor is currently available as 5mg, 10mg, 20mg, 40mg, and 80mg tablet taken whole (not split, chewed, or crushed) by mouth with or without food. Zocor does not cure your condition and only manages your symptoms. Do not discontinue taking this medication unless told otherwise by your physician.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Zocor?

Eat a low-fat, low-cholesterol diet, and follow the dietary and exercise recommendations given by your doctor.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Zocor, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Zocor, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Confusion
• Bowel movement changes (diarrhea or constipation)
• Memory loss
• Abdominal pain
• Headache
• Itching or redness of the skin

Serious side effects may include:
• Itching, hives, or rash
• Muscle pain or weakness
• Fever
• Fatigue
• Changes in appetite
• Flushing
• Abdominal pain
• Changes in the color of urine
• Yellowish discoloration of the skin or eyes
• Yellowing of skin and eyes
• Flu-like symptoms
• Joint pain

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Zocor with any of the following medications:

• Amprenavir
• Atazanavir
• Azithromycin
• Biaxin
• Boceprevir
• Cardizem
• Ceritinib
• Chloramphenicol
• Cipro
• Climara
• Colcrys
• Cordarone
• Coumadin
• Crestor
• Danazol
• Diflucan
• Erythromycin
• Flagyl
• Gemfibrozil
• Hydralazine
• Invokana
• Isoptin
• Lopid
• Lofibra
• Mifepristone
• Mipomersen
• Nizoral
• Norvasc
• Pravachol
• Premarin
• Prempro
• Prograf
• Protonix
• Provera
• Ranexa
• Rapamune
• Restasis
• Simeprevir
• Sporanox
• St. John’s wort
• Vfend
• Vivelle dot
• Zidovudine

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Zocor in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Simvastatin is contraindicated for use in pregnant women, women trying to get pregnant, or are breastfeeding. Hence, the potential risks and benefits of using Zocor in pregnant or breastfeeding infants should be carefully considered.

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