Why is Zoloft prescribed?

Zoloft, with generic name Sertraline Hydrochloride, is used to manage symptoms of depression, obsessive-compulsive disorder, post-traumatic stress disorder, and anxiety disorders (social anxiety disorder and panic disorder). It is also prescribed to manage premenstrual dysphoric disorder symptoms like breast tenderness, bloating, irritability, and mood swings.

Depression is a mood disorder that affects the behavior and way of thinking of an individual causing a persistent loss of interest and sadness that affects daily functioning. While obsessive-compulsive disorder is a condition where persistent bothersome thoughts cause repetitive behaviors.

Post-traumatic stress disorder (PTSD) is a condition that results from a frightening experience that causes a disturbance in daily activities. Social anxiety, on the other hand, is a disorder where there is an extreme fear of social interactions, while panic disorder is a condition where there are sudden attacks of extreme fear.

What does it do?

Sertraline Hydrochloride, classified under selective serotonin reuptake inhibitors (SSRIs), increase the levels of certain substances (serotonin and norepinephrine), that regulate mood and mental balance.

How should I take it?

Zoloft is currently available as 25mg, 50mg, and 100mg tablets taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Zoloft?

Zoloft is known to cause drowsiness. Avoid driving or operating heavy machinery while taking this medication. Avoid the intake of alcohol as this could exacerbate drowsiness.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Zoloft, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Zoloft, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Changes in bowel movement
• Appetite changes
• Fatigue
• Dizziness
• Dry mouth
• Drowsiness
• Excessive sweating
• Changes in libido
• Spasms in any part of the body
• Weight changes
• Vomiting
• Headache
• Anxiety

Serious side effects may include:
• Itching, hives, or rash
• Swelling on any part of the face
• Hoarseness
• Difficulty breathing or swallowing
• Rapid or irregular heartbeat
• Muscle stiffness
• Seizures
• Unusual bleeding
• Easy bruising
• Incoordination
• Loss of consciousness
• Agitation

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Zoloft with any of the following medications:

• Abilify
• Adderall
• Ambien
• Amitriptyline
• Aspirin
• Ativan
• Azilect
• Benadryl
• Celexa
• Clonazepam
• Cymbalta
• DDAVP
• Effexor
• Gabapentin
• Granisetron
• Ibuprofen
• Lexapro
• Lithium
• Nizoral
• Lyrica
• Meperidine
• Mirtazapine
• Neurontin
• Paxil
• Percocet
• Phentermine
• Pristiq
• Prozac
• Ondansetron
• Ozanimod
• Remeron
• Rexulti
• Seroquel
• St. John’s wort
• Suboxone
• Topamax
• Tramadol
• Trazodone
• Vyvanse
• Wellbutrin
• Wellbutrin XL
• Xanax
• Zolmitriptan

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Zoloft in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Sertraline is not recommended for use in pregnant women, women trying to get pregnant, or are breastfeeding, and should only be used if the benefits outweigh the risks associated with the use of this medication. Hence, the potential risks and benefits of using Zoloft in pregnant or breastfeeding infants should be carefully considered.

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