Why is Zomig prescribed?

Zomig, with generic name Zolmitriptan, is used to manage symptoms of migraine headaches, often described as a severe throbbing or pulsating headache associated with nausea, vomiting, or light and sound sensitivity.

What does it do?

Zolmitriptan is classified as a selective serotonin receptor agonist, which narrows the blood vessels on the brain, preventing pain signals to reach the brain, and halts the release of certain substances that causes the symptoms associated with migraine headaches.

How should I use it?

Zomig is currently available as 2.5mg and 5mg tablets (Zomig) taken whole (not split, chewed, or crushed) by mouth with or without food. It is also available as 2.5mg and 5mg orally disintegrating tablets (Zomig Rapimelt/Zomig-ZMT) taken whole (not split, chewed, crushed, or swallowed) by mouth and allowed to dissolve.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The proper use of medications is needed to achieve the desired effect of any drug. As much as possible, strictly follow your doctor’s prescribed dosing schedule. If you miss a dose, take it immediately. However, if it’s close to the next scheduled dose, skip the missed dose and proceed with the regular dosing schedule. Never take two doses at the same time to make up for a missed dose, unless told otherwise.

What are the special precautions before using Zomig?

Zomig is known to cause drowsiness. Avoid driving or operating heavy machinery while taking this medication. Avoid the intake of alcohol as this could exacerbate drowsiness.

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Zomig or Zomig Rapimelt, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Zomig and Zomig Rapimelt/Zomig-ZMT, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Heat or cold intolerance
• Drowsiness
• Dry mouth
• Nausea
• Heartburn
• Sweating
• Dizziness
• Loss of consciousness

Serious side effects include:
• Itching, hives, or rash
• Swelling on any part of the face
• Hoarseness
• Difficulty breathing or swallowing
• Rapid or irregular heartbeat
• Slurring of speech
• Bloody stools
• Sudden, severe abdominal pain
• Pale or bluish nailbeds or lips

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Zomig or Zomig Rapimelt with any of the following medications:

• Acebutolol
• Atazanavir
• Bromocriptine
• Cabergoline
• Cardizem
• Celexa
• Cipro
• Climara
• Coreg
• Cymbalta
• Ditropan
• Effexor
• Fentanyl
• Granisetron
• Hydrocodone
• Isocarboxazid
• Lasmiditan
• Lexapro
• Morphine
• Naratriptan
• Nefazodone
• Ondansetron
• Ozanimod
• Plan B
• Premarin
• Prempro
• Pristiq
• Provera
• Rizatriptan
• St. John’s wort
• Sumatriptan
• Tapentadol
• Toprol
• Tramadol
• Trazodone
• Vivelle dot
• Vortioxetine
• Zebeta
• Zoloft

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Keep Zomig or Zomig Rapimelt in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Caution is recommended when Zomig or Zomig Rapimelt is used by pregnant women, women trying to get pregnant, or are breastfeeding, and should only be used if the benefits outweigh the risks associated with the use of this medication. Hence, it is essential to consider both the developmental and health benefits of breastfeeding, along with the mother’s clinical need for this medication.

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