NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Orap prescribed?

Orap (Pimozide) is primarily prescribed to suppress sudden movements and vocal tics associated with Tourette's syndrome.

What does it do?

Orap (Pimozide) works by blocking dopamine receptors in the brain, which reduces the activity of this neurotransmitter. This lowers the effect of dopamine in the body and the severity of tics for individuals that have Tourette's syndrome.

How should I take it?

Orap (Pimozide) should be taken exactly as prescribed by your healthcare provider. Take it at the same time each day to maintain consistent levels in your system, and do not adjust the amount or frequency without consulting your doctor. Orap is initially taken as 1 to 2 mg orally per day in divided doses with a full glass of water, with or without food. The maintenance dose is typically below 0.2 mg per kilogram of body weight per day, or a maximum of 10 mg per day, whichever is lower.

Continue taking Orap as prescribed by your healthcare provider, even if you start feeling better. Stopping suddenly may cause withdrawal symptoms or worsen your condition.

What if I missed a dose?

If you miss a dose of Orap, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

What are the special precautions before taking Orap?

Inform your doctor about all the medications you are taking, your current and previous medical history and before taking Orap, here are several important precautions to keep in mind:

• Avoid taking Orap if you have a history of heart problems, such as arrhythmias, bradycardia, or QT prolongation, as it can increase the risk of severe heart issues.
• Do not take Orap if you are allergic to Pimozide or any of the other ingredients in the medication.
• Do not share this medication with others, even if they have the same condition, as it could potentially be harmful to them.
• Discuss with your doctor if you have liver or kidney issues, as these conditions may affect how your body processes the medication.
• Orap (Pimozide) is generally not recommended during pregnancy and breastfeeding unless absolutely necessary or prescribed by a doctor.
• Share your full medical history with your doctor, including any history of seizures, mental health conditions, or other significant health concerns

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Blurred vision
• Drowsiness or dizziness
• Dry mouth
• Constipation
• Headache
• Tight muscles or weakness

Serious side effects may include:
• Difficulty breathing
• Uncontrolled muscle movements
• Fast or irregular heartbeat
• Seizures
• High fever
• Swelling of the face, lips, mouth, tongue, or throat

This is not a complete list of all possible side effects, and others may occur. For more information about side effects, please consult your healthcare provider.

Is it safe to take it with another drug?

Orap (Pimozide) may interact with other medications, so it's important to take caution before combining it with other drugs like:

• Antiarrhythmic agents
• Phenothiazines
• Sotalol
• Quinidine
• Moxifloxacin
• Sparfloxacin
• Tacrolimus
• Thioridazine

Orap (Pimozide) may lead to serious heart issues, especially if combined with certain medications for infections, asthma, cardiovascular conditions, high blood pressure, mental health disorders, cancer, malaria, or HIV. Furthermore, its sedative effects can intensify when taken with drugs that cause drowsiness, such as opioids, sleep aids, muscle relaxants, and seizure medications.

Note that this is not the complete list and it's important to always consult your healthcare provider before combining Oralair with other medications to ensure safety.

How should I store it?

Orap should be stored in its original packaging at room temperature, ideally between 20°C and 25°C (68°F and 77°F). Keep it away from direct sunlight and out of reach of children and pets. Always refer to the medication's packaging for any specific storage guidelines and avoid using it beyond the expiration date.

What action should I take in case of overdose?

If you suspect an overdose of Orap (Pimozide), it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Symptoms of overdose may include severe drowsiness, dizziness, irregular heartbeat, muscle stiffness, or difficulty breathing.

Is it safe for pregnant or breastfeeding women?

Orap (Pimozide) is not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the risks. This medication should only be used during pregnancy if absolutely necessary, as infants born to mothers who used this medication during the final trimester of pregnancy may occasionally exhibit symptoms such as muscle stiffness or tremors, drowsiness, difficulties with feeding or breathing, or persistent crying.

On the other hand, the safety of Orap during breastfeeding is not well established. It is unknown whether the drug passes into human milk, but it may cause side effects like hyperprolactinemia, which could affect milk production. It's important to consult your doctor if you're pregnant or breastfeeding before using the medication to ensure safety.

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