NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Vyzulta prescribed?

Vyzulta (Latanoprostene Bunod) is frequently prescribed to lower elevated eye pressure in individuals with open-angle glaucoma or ocular hypertension.

What does it do?

Vyzulta (Latanoprostene Bunod) is a prostaglandin that reduces eye pressure by helping to drain fluid from the eye.

How should I take it?

Use this medicine exactly as prescribed by your doctor. Do not apply more of it, do not use it more frequently, and do not use it for a longer period than instructed. Doing so may increase the risk of side effects.

Do not use the eye drops if you are wearing contact lenses. Remove your contact lenses before applying the medicine, and wait at least 15 minutes after use before reinserting them. If you are using other eye medications along with Vyzulta eye drops, make sure to space them at least 5 minutes apart.

What if I missed a dose?

If you miss to take Vyzulta, take it as soon as you remember.Do not take two doses at once.

What are the special precautions before taking Vyzulta?

Inform your healthcare provider about all of your health conditions, as well as any prescription or other supplements you are taking. This will help them determine if Vyzulta is appropriate for you.

Specifically, make sure to discuss the following your current and past health conditions:

• Allergies
• A history of eye surgery
• Any eye conditions, including uveitis or problems with your eye lens
• Diabetes
Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions.
Common side effects may include:
• Eye irritation or discomfort
• Redness in and around the eyes
• Pain in the eye where the drops are applied
Serious side effects may include:

Severe Allergic Reactions: Vyzulta can cause serious allergic reactions. Stop using the medication and seek help right away if you have any of the following symptoms:

• Breathing difficulties or wheezing
• Rapid heartbeat
• Fever or general malaise
• Swollen lymph nodes
• Swelling of the face
• Difficulty swallowing or a tight throat

Increased Brown Coloring of the Iris: Vyzulta may cause the iris (the colored part of your eye) to gradually darken. This change can take months or even years to develop and may be permanent, even after stopping the medication.

Eyelash Changes: Vyzulta may alter your eyelashes, including increased length, color, thickness, shape, and number. These changes usually return to normal after stopping the medication.

Macular Edema: Vyzulta can cause macular edema, which is swelling in part of the retina that can affect your vision. If you notice any changes in your vision, contact your healthcare provider immediately.

Other side effects of Vyzulta may occur that are not listed here. If you believe you're experiencing a side effect, contact your healthcare provider.

Is it safe to take it with another drug?
There are no known interactions between Vyzulta and other medications. Be sure to inform your healthcare provider about any prescription or other supplements you are taking.
How should I store it?
Keep the unopened bottle of Vyzulta in the refrigerator, between 36°F and 46°F (2°C to 8°C). Once the bottle is opened, it can be stored either in the refrigerator or at room temperature, between 36°F and 77°F (2°C to 25°C), for up to 8 weeks. Protect from light and do not freeze. During shipment, it may be maintained at temperatures up to 40°C (104°F) for a period not exceeding 14 days.
What action should I take in case of overdose?
If you or someone else has used too much Vyzulta, seek medical help immediately by calling your doctor or going to the nearest emergency department.
Is it safe for pregnant or breastfeeding women?

Pregnancy: The effects of Vyzulta on pregnancy or its potential risk to an unborn baby are not known. Inform your doctor if you are pregnant or planning to become pregnant.

Breastfeeding: It is unclear whether Vyzulta is passed into breast milk. Let your doctor provider know if you are breastfeeding or intend to breastfeed, and they will guide you on whether to use Vyzulta during this time.

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