Aprinox are used to treat hypertension (high blood pressure) and oedema (fluid retention). They are also prescribed to stop breast milk production.

What does it do?

Aprinox (Bendroflumethiazide) works by helping the kidneys eliminate excess salt and water, which reduces fluid in the blood vessels and tissues. This helps lower blood pressure and decrease swelling. Additionally, it relaxes blood vessels, making it easier for the heart to pump blood, and prevents excessive salt retention, which can contribute to high blood pressure and fluid buildup.

How should I take it?

Always take your medication exactly as prescribed by your doctor. If you’re unsure, consult your doctor or pharmacist.

Commonly prescribed doses are as follows, though your doctor may adjust them based on your individual needs:

• High blood pressure: Typically, 2.5 mg once daily in the morning. Higher doses are rarely needed.
• Fluid retention: Starting dose is 5 to 10 mg daily or every other day. Maintenance dose is 5 to 10 mg one to three times a week.
• Suppression of breast milk: Usually 5 mg in the morning and 5 mg at midday for about five days.
• Children: The dose depends on the child’s weight. Starting dose is up to 400mcg per kg of body weight, with a maintenance dose of 50-100mcg per kg of body weight. Your doctor will specify the correct dosage.
• Elderly: The dose may need to be lowered in older patients, particularly if there is a risk of salt imbalance in the blood.

Your doctor will determine the appropriate dose for you or your child.

What if I missed a dose?
If you miss a dose, simply take the next dose at your usual time. Do not take two doses at once.
What are the special precautions before taking Aprinox?
Your doctor may monitor your condition with regular blood tests, particularly if you are elderly or taking the medication for a long period. Take special care and tell your doctor or pharmacist if you:
• Diabetic
• Have gout
• Have or had systemic lupus erythematosus
• Have mild to moderate kidney or liver disease (your doctor may want to monitor you more closely)
• Suffer from alcoholic cirrhosis

If you see another doctor or visit a hospital, always inform them of any medications you are currently taking. Before having surgery, let your anaesthetist know you're taking Aprinox 2.5 mg or 5 mg Tablets, as it may interact with some anaesthesia drugs.

If you are being treated for depression with tricyclic antidepressants (like amitriptyline), be aware that there may be an increased risk of low blood pressure when standing while taking Aprinox.

Does it have any side effects?

Like all medications, Aprinox may cause side effects in some people, although it is generally well tolerated. If you experience any of the following, contact your doctor immediately:

Serious side effects may include:
• Hypersensitivity reactions, such as severe skin reactions, swelling of the face, tongue, lips, or lung inflammation (pneumonitis), throat (which may cause difficulty breathing or swallowing), or fluid retention in the lungs (pulmonary oedema).
• Unusual bruising or bleeding, unexplained tiredness, or more frequent infections (e.g., colds or sore throats). Your doctor may want to monitor your blood periodically.
Other potential side effects include:
• Blood sugar changes, as with other diuretics
• Light sensitivity, Skin rashes, blood disorders (including anemia)
• Increased uric acid levels in the blood, which can cause joint swelling (gout)
• Issues with the pancreas or liver
• Dizziness or faintness when standing, possibly due to low blood pressure
• Occasional impotence, which is usually reversible after stopping the medication
If any side effects become severe or if you notice any side effects not listed, contact your doctor or pharmacist immediately.
Is it safe to take it with another drug?
Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Aprinox with any of the following medications: Inform your doctor if you are taking any other medications, especially the following:
• Antibiotics, like amphotericin
• Acetazolamide (used for glaucoma), ACTH (corticotropin), or carbenoxolone (used for ulcers)
• Asthma treatments, such as theophylline
• Allergy medications, like terfenadine
• Diuretics and alpha blockers (e.g., prazosin)
• Barbiturates (e.g., phenobarbital), used for conditions like severe insomnia or epilepsy
• Opioid pain medications, such as codeine or diamorphine
• Medicines to reduce inflammation, like corticosteroids
• Epilepsy treatments, such as carbamazepine
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Moxisylyte, used for Raynaud’s syndrome
Make sure to inform your doctor about all medicines you are taking to avoid any potential interactions.
How should I store it?
Store below 25°C. Keep the container tightly closed and in its original packaging. Do not use after the expiration date printed on the carton.
What action should I take in case of overdose?
Overdose symptoms of Bendroflumethiazide are confusion, dizziness and uncontrolled body shaking contact a doctor immediately or go to the nearest emergency department.
Is it safe for pregnant or breastfeeding women?

Aprinox (Bendroflumethiazide) is generally not recommended for use during pregnancy, as it may harm an unborn baby. It is important to discuss any potential risks with your doctor if you are pregnant or planning to become pregnant. As for breastfeeding, it is also not recommended to use Aprinox while breastfeeding, as it is not clear whether the drug passes into breast milk. You should consult your doctor to explore safer alternatives if you're breastfeeding.

Why buy Aprinox online from Canada?

Canadian Prescription Drugstore is a 5-star rated online Canadian pharmacy service that offers the best quality prescription drugs at discounted prices.

Buy Canada drugs with confidence from the most trusted online Canadian pharmacy for over 15 years.

Get FREE SHIPPING for your online medication orders from our Canadian pharmacy (valid for first-time orders only).

For more information, visit Canadian Prescription Drugstore.