Why is Arixtra prescribed?

Arixtra (Fondaparinux) is used to prevent blood clots following certain hip, knee, or abdominal surgeries. It can also be used to treat blood clots in the legs or lungs when combined with another medication called warfarin.

What does it do?

Fondaparinux is an anticoagulant, or blood thinner. It works by blocking specific substances in the blood that contribute to clot formation.

How should I take it?

This medicine is administered through an injection under the skin, typically given by a healthcare professional in a hospital or clinic.

If you're receiving this medicine at home, you'll be instructed on how to prepare and administer it. Follow the directions carefully and take your medicine at the prescribed intervals. Do not take it more frequently than directed, and only stop using it if advised by your doctor, as stopping may increase your risk of a blood clot. Be sure to refill your prescription before running out.

It’s important to dispose of used needles and syringes in a proper sharps container. Never throw them in the trash. If you don't have a sharps container, contact your pharmacist or healthcare provider to obtain one.

What if I missed a dose?

If you miss a dose, take it as soon as you remember. Do not take two doses at once.

What are the special precautions before taking Arixtra?

Inform your doctor about all the medications you are taking, your current and previous medical history. It is advised to monitor Arixtra as increases the risk of bleeding and asses renal function while on this medication.

You cannot use Arixtra to prevent clots if you weigh less than 50kg or 110 lbs.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions.

Common side effects may include:
• Signs of bleeding
• Redness, pain, or irritation at the injection site
Serious side effects may include:
• Allergic reactions
• Severe bleeding
• Blood clot
This list may not cover all possible side effects. Contact your doctor for medical advice if you experience any side effects.
Is it safe to take it with another drug?

Some drug interactions may cause serious or life-threatening reactions when administered together. Immediately inform your doctor if you are taking Arixtra with any of the following medications:

Do not take this medication with any of the following:
• Aspirin and aspirin-like medicines
• Heparin
• Mifepristone
• Warfarin
This medication may also interact with the following:
• Anti-inflammatory drugs such as ibuprofen
• Cilostazol
• Clopidogrel
• Dipyridamole
• Sulfinpyrazone
• Ticlopidine

This list may not cover all possible interactions. Be sure to provide your healthcare provider with a complete list of all the medications.

How should I store it?
Store it at room temperature, between 15°C and 30°C (59°F and 86°F). Do not freeze. Discard any unused medicine after the expiration date. Keep this medication out of the reach of children.
What action should I take in case of overdose?
Overdose of Arixtra (Fondaparinux) may cause hemorrhagic problems, immediately discontinue and seek medical help or go to the nearest hospital.
Is it safe for pregnant or breastfeeding women?

Pregnancy: Fondaparinux may harm an unborn baby. Inform your healthcare provider if you are pregnant or planning to become pregnant. They will guide you on the safest way to treat or prevent blood clots during pregnancy.

Breastfeeding: It is unclear whether Fondaparinux passes into breast milk. Let your healthcare provider know if you are breastfeeding or planning to breastfeed. They will advise you on whether it is safe to use fondaparinux while breast feeding.

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