Artane (Trihexyphenidyl) is commonly prescribed to manage symptoms of Parkinson's disease, which affects the brain's movement control center. It can also be used to treat involuntary movements that may result as side effects from certain medications.

What does it do?

Artane (Trihexyphenidyl) works by reducing the activity of the parasympathetic nervous system, which regulates automatic functions in the body such as digestion and breathing. Additionally, it helps relax the muscles.

How should I take it?

Take Artane exactly as prescribed by your doctor. If you have any questions about the instructions, ask your pharmacist, nurse, or doctor for clarification. Take each dose with a full glass of water. Artane can be taken with or without food. Taking it with food may help reduce stomach discomfort.

What if I missed a dose?

If you miss a dose, take it as soon as possible. However, if it's nearly time for your next dose, skip the missed dose and just take the scheduled one. Do not double dose.

What are the special precautions before taking Artane?

Inform your doctor about all the medications you are taking, your current and previous medical history.

Before using Artane, consult your doctor if you have:

• A history of allergic reactions to it
• Bowel obstruction or megacolon
• Narrow-angle glaucoma
• Myasthenia gravis

Additionally, inform your doctor if you have:

• Epilepsy or other seizure disorders
• Prostate enlargement or difficulty urinating
• Heart disease or irregular heartbeat
• Depression or other psychiatric conditions
• Kidney or liver disease

Be cautious when driving, operating machinery, or engaging in hazardous activities, as Artane may cause dizziness or blurred vision. If you experience these side effects, avoid these activities.

Drink alcohol cautiously, as it can increase drowsiness and dizziness while taking Artane and avoid high temperature areas, as Artane may reduce sweating, which can increase the risk of heat stroke in hot weather or during vigorous exercise.

These conditions may require a dosage adjustment or special monitoring during treatment.

Does it have any side effects?
It is important to note that all drugs have corresponding side effects and adverse reactions.
• Allergic reactions such as itching or hives, skin rash, swelling of the lips, face, or tongue
• Vomiting
• Hallucinations
• Changes in vision
• Rapid or irregular heartbeat

Side effects that typically don’t require medical attention (but should be reported to your doctor if they persist or become bothersome) include:

• Anxiety or nervousness
• Dizziness
• Drowsiness
• Nausea
This list may not include all possible side effects. Contact your doctor for medical advice if you experience any side effects.
Is it safe to take it with another drug?

Always inform your healthcare provider about any prescription or over-the-counter medications, vitamins, minerals, herbal products, and other supplements you're taking. In particular, let your healthcare provider know if you are using any of the following before taking Trihexyphenidyl:

• Barbiturates (e.g., butalbital, phenobarbital, primidone), used to treat insomnia, migraines, or seizures
• Opioids (e.g., morphine, codeine, oxycodone, fentanyl), used for certain types of pain
• Monoamine oxidase inhibitors (MAOIs), typically used for depression or Parkinson’s disease
• Tricyclic antidepressants (e.g., nortriptyline, amitriptyline, protriptyline), even if not used for depression
• Any other medication that causes dizziness or drowsiness, such as sleep aids, pain medications, or anxiety treatments
This may not be a complete list of medications that could interact with Trihexyphenidyl. Always consult your healthcare provider for further information.
How should I store it?
Store at room temperature, between 15 and 30°C (59 and 86°F). Keep it out of reach of children.
What action should I take in case of overdose?
Some symptoms of overdose of this medication are flushed face, irregular heartbeat, loss of consciousness; and seizures contact your doctor or go to the emergency room immediately.
Is it safe for pregnant or breastfeeding women?

Pregnancy: The effects of trihexyphenidyl on pregnancy or an unborn baby are not known. Consult your healthcare provider if you are pregnant or planning to become pregnant for guidance on whether to take the medication.

Breastfeeding: It is unclear if trihexyphenidyl passes into breast milk. Inform your healthcare provider if you are breastfeeding or planning to breastfeed, so they can advise you on whether to continue breastfeeding or stop taking the medication.

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