Why is Calcort prescribed?

Deflazacort (Calcort) is prescribed for the management of Duchenne muscular dystrophy to improve the strength of muscles. It is also being used for the treatment of kidney problems, eye problems, asthma, arthritis and abnormal growth tumors in the body.

What does it do?

Deflazacort, classified as a corticosteroid, is being converted to its active metabolite, 21-Deflazacort, to exert its effect. It primarily works by promoting anti-inflammation and immunosuppression effects in the glucocorticoid receptor; thus, helping the body to increase resistance to autoimmune diseases and maintain healthy well-being.

How should I take it?

Calcort is currently available as a 30mg tablet that should be taken as a whole (do not split) by mouth with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Calcort?

Before taking Deflazacort, tell your doctor or pharmacist if you have any allergies to food or to the drug itself as it may contain several inactive ingredients, which can cause allergic reactions or problems.

Inform your doctor about your past and current medical history, especially if you have or have had high blood pressure, kidney disease, liver disease, fluid retention, intestinal disorder, glaucoma, cataracts, diabetes, problems in the thyroid and pituitary glands, ileostomy, colostomy and myasthenia gravis.

Consult your doctor regarding all the other medications you use before getting surgery.

For the drug label information of Deflazacort, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Hirsutism
• Increased appetite
• Insomnia 
• Sneezing
• Soreness of throat
• Urge to urinate
• Weight gain

Serious side effects include:
• Blurred vision
• Chills
• Constipation
• Decreased libido
• Diarrhea
• Dysrhythmia
• Fever
• Fluttering of chest
• Hallucinations
• High blood pressure
• Light-headedness
• Menstrual cycles changes
• Muscle weakness
• Syncope

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Calcort with any of the following medications:

• Abametapir
• Amobarbital
• Ampicillin 
• Anthrax vaccine
• Apalutamide
• Aspilet
• Auvi-Q
• BCG vaccine live
• Butabarbital
• Carbatrol
• Castor oil
• Celcoxx
• Celebrex
• Cholestyramine
• Chloramphenicol
• Claritin
• Clobazam
• Conivaptan
• Diflucan
• Dilantin
• Dilzem
• Dronedarone
• Dulcolax
• Ephedrine
• Fosphenytion
• Heparin Leo
• Hepatitis A vaccine, inactivated
• Indocin
• Ivosidenib
• Lactulose
• Lilac
• Lipitor
• Luminal
• Mevacor
• Mifepristone
• Mitotane
• Nevirapine
• Plendil
• Primidone
• Quinidine
• Rubella vaccine
• Ventolin
• Voltaren

If you are using any prescription, non-prescription and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Calcort at room temperature (25°C) in a clean environment away from light and moisture, as well as children and pets. Do not refrigerate. Do not remove the desiccant in the original container. Throw away if unused or expired. Do not flush in the toilet. Consult the pharmacist for proper disposal.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

There are only limited studies and data regarding the safety of Deflazacort to determine drug-associated risks of major maternal defects, miscarriages and fetal outcomes.

Limited data have been established indicating the presence of Deflazacort in human milk. Consult your doctor first before breastfeeding.

The use of Deflazacort in pregnant and breastfeeding women should be avoided unless the potential benefits outweigh the risks.

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