Why is Differin prescribed?

Adapalene (Differin) cream is prescribed for the treatment of acne vulgaris. It can be applied to acne found on the face, chest, or back. It is best used on dry and fair skin.

What does it do?

Acne vulgaris is a condition where the hair follicles on your skin become blocked with dirt, oil, and dead skin cells causing pimples, whiteheads, and blackheads. Differin belongs to a drug class called retinoids and it reduces the amount and severity of your acne. It works by preventing the formation of pimples.

How should I apply it?

Differin and its generic equivalents are currently available as a 0.1% cream, applied only to the skin. Avoid getting Differin cream into your eyes or mouth.

Wash your hands thoroughly before and after handling the medication. Clean the area to be treated with a mild or soapless cleanser and pat dry. Apply a thin layer of the medication onto the area to be treated. If your skin becomes dry, you may use a skin moisturizer. However, you should use moisturizers that do not contain alpha hydroxyl or glycolic acids. Follow the instructions that come with the medication and consult your doctor or pharmacist for any concerns you may have.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if used properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, apply it immediately and adjust the time of your next dose depending on your doctor’s advice. Never apply two doses at the same time just to make up for your missed dose.

What are the special precautions before applying Differin?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Differin or any other ingredients included in the manufacture of this medication.

Do not apply Differin cream to cuts or broken, sunburned, or eczematous skin.

When first using Differin cream, your acne may worsen. Continue using the medication and do not discontinue it without consulting your doctor.

Using Differin cream may cause your skin to be more sensitive to sunlight or extreme weather. Avoid exposing yourself to these conditions and wear protective clothing, sunscreen, and use sunglasses when going outdoors.

Differin cream should not be used by children and in people younger than 12 years of age.

For the drug label information of Differin, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Burning or warm sensation on the skin
• Pain on the skin
• Peeling and dryness of the skin
• Redness
• Skin irritation

Serious side effects include:
• Difficulty breathing
• Rashes
• Severe itching
• Severe redness, burning and peeling of the skin after exposure to the sun or extreme weather
• Swollen face, lips, tongue, or throat

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Differin with any of the following medications:

• Duac gel
• Isotretinoin
• Methoxsalen
• Methyl aminolevulinate
• Porfimer
• Resorcinol
• Salicylic acid
• Topical sulfur
• Verteporfin

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Differin in its container in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Differin in pregnant women has not established its developmental risks.

There is also limited data on the presence of Differin in human milk or its effects on the breastfed infant. Hence, the potential risks and benefits of using Differin in pregnant or breastfeeding women should be carefully considered.

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