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Why is Monurol prescribed?

Monurol (Fosfomycin Tromethamine) sachet is an antibiotic prescribed for treating uncomplicated urinary tract infections (UTIs), such as acute cystitis, in women. It's particularly effective against infections caused by Escherichia coli and Enterococcus faecalis.

What does it do?

Monurol (Fosfomycin Tromethamine) works by inhibiting bacterial cell wall synthesis. It interferes with the formation of peptidoglycan, a key component of the bacterial cell wall, which ultimately leads to bacterial cell death. This makes it a bactericidal antibiotic, meaning it kills the bacteria rather than just inhibiting their growth.

How should I take it?

For women aged 18 and older with uncomplicated urinary tract infections (acute cystitis), the recommended dose is one sachet of Monurol. Monurol can be taken with or without food. To take, dissolve one sachet (3 grams) in 3-4 ounces (about 120 milliliters) of cold water and drink immediately.

What if I missed a dose?

Given that Monurol (Fosfomycin Tromethamine) is generally prescribed as a single-dose treatment, missing a dose is usually not a major issue. However, if you realize you haven't taken it within the recommended timeframe, please contact your doctor for further guidance.

What are the special precautions before taking Monurol?

Before taking Monurol (Fosfomycin Tromethamine), there are several special precautions to keep in mind:

• Do not take Monurol if you are allergic to fosfomycin trometamol or any of the other ingredients in the medication.
• The medicine should not be given to children under 12 years old, as its safety and effectiveness have not been established for this age group.
• Symptoms should improve within 2-3 days. If symptoms persist or worsen, it's important to contact your doctor for medical advice.
• If you have severe kidney problems (creatinine clearance below 10 ml/min) or are on hemodialysis, talk to your doctor before taking Monurol.
• Let your doctor know if you have any other medical conditions, especially if you have had diarrhea after taking antibiotics or have sugar intolerance.

It's always best to discuss these precautions with your doctor to ensure Monurol is safe and appropriate for you.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Diarrhea
• Dizziness
• Headache
• Nausea
• Fatigue
• Menstrual pain
• Vaginal discomfort or unusual discharge

Serious side effects may include:
• Severe diarrhea (watery or bloody)
• Burning or painful urination
• Difficulty breathing
• Signs of allergic reaction (swelling of the lips, face, tongue, or throat)

This list of side effects is not complete, and other effects may occur. Before taking Monurol, consult your doctor for medical advice about potential side effects.

Is it safe to take it with another drug?

Monurol (Fosfomycin Tromethamine) can interact with certain other medications. It's important to tell your doctor about all the medications you are taking. Some known interactions include:

• Metoclopramide: This medication can interfere with the effectiveness of Monurol (Fosfomycin Tromethamine) by increasing gastrointestinal motility, which lowers the serum concentration and urinary excretion of Monurol.
• Live bacterial vaccines: Such as cholera vaccine and typhoid vaccine.

Always consult your healthcare provider before starting any new medication to check for possible interactions.

How should I store it?

Store the medication at room temperature, away from moisture and heat. Keep the sachets in their original blister pack until you are ready to use them, and they should be kept out of reach of children and pets.

What action should I take in case of overdose?

Overdosing on antibiotics can lead to serious side effects, so it's important to act quickly. In case of an overdose of Monurol (Fosfomycin Tromethamine), it's crucial to seek medical attention immediately.

Is it safe for pregnant or breastfeeding women?

Monurol (Fosfomycin Tromethamine) should be used during pregnancy only if prescribed by your doctor. The safety of this medication during pregnancy has not been fully established.

As for breastfeeding, it's unknown if fosfomycin passes into breast milk. It's important to consult your doctor before breastfeeding while taking this medication.

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