NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Nurtec ODT (Rimegepant) is often used to treat the following conditions.

• Treatment of migraines, with or without aura. An aura can occur before or during a migraine and may include sensory disturbances such as seeing flashing lights or zigzag patterns, difficulty speaking, or a tingling sensation.
• Prevention of episodic migraines, which are defined as migraine attacks occurring between 1 and 14 times per month.
What does it do?

Nurtec ODT works by inhibiting a substance in the brain known as calcitonin gene-related peptide (CGRP), which plays a role in headache pain and can prolong migraines. By blocking CGRP, Nurtec ODT helps prevent and treat migraines.

How should I take it?

Nurtec ODT can be taken once daily as needed to treat an acute migraine, but no more than one tablet should be taken within a 24-hour period. For the prevention of episodic migraines, Nurtec ODT can be taken every other day. The safety of using more than 18 doses in a thirty (30) day period has not been established. Be sure to follow all instructions on the medication label and packaging.

What if I missed a dose?

If you're using Nurtec ODT to prevent migraines and miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and take the next one as scheduled.

If you're using Nurtec ODT to treat a migraine, it should be taken only as needed, according to your doctor’s instructions. Do not take double or extra doses.

What are the special precautions before taking Nurtec ODT?

Inform your doctor about all your health conditions, as well as any prescription or over-the-counter (OTC) medications, vitamins, minerals, herbal products, and other supplements you are taking. This will help them assess whether Nurtec ODT is right for you.

Current and past Health Conditions: Inform your healthcare provider if you have any of the following.

• Kidney problems
• Liver problems

Liver Problems: Nurtec ODT should not be used if your liver is not functioning properly. If there are concerns about your liver health, your healthcare provider may conduct tests to assess whether it is functioning well enough to safely take this medication.

Individuals who are allergic to any of the ingredients should not take Nurtec ODT medication.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

The most usual side effect of Nurtec ODT when used for the acute treatment of migraine attacks, with or without aura:

• Nausea
The most usual side effects of Nurtec ODT in preventive treatment of episodic migraine are:
• Stomach pain
• Nausea
• Indigestion
Serious side effects may include:

Allergic reactions. Allergic reactions, such as difficulty breathing and rash, can occur after taking Nurtec ODT, sometimes days later. If you experience any of the following symptoms, which may indicate an allergic reaction, contact your healthcare provider or seek emergency medical help immediately:

• Swelling of the face, throat, or tongue
• Trouble breathing
The most usual side effect of Nurtec ODT when used for the acute treatment of migraine attacks, with or without aura:
• Nausea
The most usual side effects of Nurtec ODT in preventive treatment of episodic migraine are:
• Indigestion
• Stomach pain
• Nausea
These are not all the possible side effects of Nurtec ODT. For medical advice regarding side effects, contact your doctor.
Is it safe to take it with another drug?

Always inform your healthcare provider about any prescription or over-the-counter (OTC) medications, vitamins, minerals, herbal products, or other supplements you are taking.

• Fluconazole (Diflucan) or itraconazole (Sporanox, Tolsura), medications used to treat fungal infections.
• Cyclosporine (Gengraf, Neoral, Sandimmune, and others), a medication used to suppress the immune system.
• Lapatinib (Tykerb), a medication used to treat certain types of breast cancer.
• Amiodarone (Pacerone and others) or quinidine, medications used to treat irregular heart rhythms.
• Rifampin, a medication commonly used to treat tuberculosis infections.
• Ranolazine (Aspruzyo Sprinkle), a medication used to treat chest pain.
Many other medications can affect the blood levels of Nurtec ODT. Be sure to inform your doctor about all the medicines you are currently taking or have recently used.
How should I store it?

Nurtec ODT should be kept in its original blister pack and stored at room temperature, between 20°C to 25°C. Store in a cool, dry location, and keep out of reach of children.

What action should I take in case of overdose?

If you have taken too much Nurtec ODT, seek medical help immediately by calling your doctor or emergency department.

Is it safe for pregnant or breastfeeding women?

Pregnancy: It is not known whether Nurtec ODT can affect pregnancy or harm an unborn baby. If you are pregnant or planning to become pregnant, inform your healthcare provider.

For breastfeeding: Only very small amounts of Nurtec ODT pass into breast milk. If you are breastfeeding or planning to breastfeed, tell your healthcare provider. They will help you determine if you should take Nurtec ODT while breastfeeding.

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