Why is Onglyza prescribed?

Onglyza, with generic name Saxagliptin, is used along with diet and regular exercise to control blood sugar levels in people with type 2 Diabetes. Diabetes is a condition where the body does not produce or use insulin normally, hence causing elevations in blood sugar levels.

What does it do?

Saxagliptin belongs to a class of medications called Dipeptidyl Peptidase-4 inhibitors, which increases the amount of insulin production to control blood sugar levels.

How should I take it?

Onglyza is currently available as 2.5mg and 5mg tablets taken whole (not split, chewed, or crushed) by mouth with or without food.

The dosage strength and frequency depend on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Onglyza?

Inform your doctor about all the medications you are taking. Discuss your current and previous medical history and any allergic reactions to Onglyza, or any other ingredients included in the manufacture of this medication.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Onglyza tablets, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Headache
• Sore throat
• Joint pain
• Runny nose
• Nasal congested
• Abdominal pain

Serious side effects include:
• Itching, hives, or rash
• Muscle pain or weakness
• Fever
• Fatigue
• Changes in appetite
• Abdominal pain
• Changes in the color of urine
• Yellowish discoloration of the skin or eyes
• Flu-like symptoms

Is it safe to take it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Onglyza with any of the following medications:

• Amprenavir
• Abilify
• Atazanavir
• Bexarotene
• Captopril
• Ceritinib
• Chloramphenicol
• Climara
• Cortisone
• Delavirdine
• Diflucan
• Dopamine
• Enoxacin
• Erythromycin
• Fluvoxamine
• Geodon
• Hytone
• Insulin
• Isoptin
• Methoxamine
• Miconazole
• Nizoral
• Norgestrel
• Premarin
• Prempro
• Prograf
• Provera
• Quetiapine
• Rapamune
• Rifampin
• Risperdal
• Saquinavir
• Sporanox
• St. John’s wort
• Symbicort
• Vfend
• Vivelle dot
• Voxelotor
• Xenical
• Zafirlukast

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Keep Onglyza in its original packaging in a clean environment away from excessive heat and moisture. Keep out of reach of children.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Saxagliptin is acceptable for use in pregnant women, women trying to get pregnant, or are breastfeeding only if the benefits outweigh the risks associated with the use of this medication. Hence, the potential risks and benefits of using Onglyza in pregnant or breastfeeding infants should be carefully considered.

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