NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Orgovyx prescribed?

Orgovyx (Relugolix) is prescribed to treat advanced prostate cancer in adult men considered as hormonal therapy. The medication may also be prescribed for other conditions as determined by your healthcare provider.

What does it do?

Orgovyx works by targeting the pituitary gland in the brain. It blocks gonadotropin-releasing hormone (GnRH) receptors, which reduces the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). By reducing testosterone levels in the body, Orgovyx helps slow or halt the growth of prostate cancer cells, as they often depend on testosterone for growth.

How should I take it?

Orgovyx is taken orally as a tablet. The recommended dose for Orgovyx involves an initial loading dose of 360 mg on the first day of treatment. After that, a daily dose of 120 mg should be taken orally at roughly the same time each day.

What if I missed a dose?

If you miss a dose of Orgovyx, take it as soon as you remember. However, if it is less than 12 hours before your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

What are the special precautions before taking Orgovyx?

Inform your doctor about all the medications you are taking, your current and previous medical history.

Before taking Orgovyx, here are several important precautions to keep in mind:

• Do not take Orgovyx if you are allergic to Relugolix or any of the other ingredients in the medication.
• Tell your healthcare provider about your medical history, particularly if you have heart problems, including long QT syndrome, electrolyte imbalances, liver issues, diabetes, or anemia.
• Do not share this medication with others, even if they have the same condition, as it could potentially be harmful to them.
• Orgovyx may harm an unborn baby, so male patients with female partners who can become pregnant should use effective contraception during treatment.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Constipation
• Diarrhea
• Fatigue
• Hot flashes
• Increased blood sugar levels

Serious side effects may include:
• Difficulty breathing
• Fast or irregular heartbeats
• Unusual bleeding
• Heart attack
• Swelling of the face, lips, mouth, tongue, or throat

This is not a complete list of all possible side effects, and others may occur. For more information about side effects, please consult your healthcare provider.

Is it safe to take it with another drug?

Orgovyx (Relugolix) may interact with other medications, so it's important to take caution before combining it with other drugs.

• Oral P-gp inhibitors
• CYP3A inducers

Certain medications may increase the risk of side effects or reduce Orgovyx's effectiveness. Always seek advice from your healthcare provider before using Orgovyx alongside other medications to ensure it is safe and effective.

How should I store it?

Orgovyx should be stored in its original container at room temperature, ideally between 20°C and 25°C (68°F and 77°F). Keep it away from direct sunlight and out of reach of children and pets.

What action should I take in case of overdose?

If you suspect an overdose of Orgovyx (Relugolix), it's important to act quickly and seek immediate medical attention. Contact emergency services or go to the nearest hospital. Symptoms of overdose may include severe side effects like abnormal heart rhythms or other complications.

Is it safe for pregnant or breastfeeding women?

Orgovyx is not safe for pregnant women. It can harm an unborn baby and may cause a loss of pregnancy. Male patients with female partners who can become pregnant should use effective contraception during treatment and for at least two weeks after the last dose.

As for breastfeeding, it is unknown whether Orgovyx passes into human breast milk. Due to potential risks, breastfeeding while taking Orgovyx is generally not recommended. It's important to consult your doctor if you're pregnant or breastfeeding before using the medication to ensure safety.

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