Why is Chlorpromazine prescribed?

Chlorpromazine is prescribed for the treatment of symptoms of schizophrenia, psychotic disorders, and symptoms of mania in manic-depressive disorders. It is also used in the treatment of behavioral problems in children and hyperactivity in children. Another use for it is to control nausea and vomiting, relieve fear and nervousness before surgery, hiccups lasting longer than a month, intermittent porphyria, and in combination with other medications for the treatment of tetanus.

What does it do?

Chlorpromazine belongs to a drug class called phenothiazine antipsychotics which works by altering or bringing back the balance of natural substances in the brain and other areas of the body. It also has sedative (calming and sleep-inducing) and anti-emetic (prevents nausea and vomiting) effects.

How should I take it?

Chlorpromazine is currently available in 50mg tablets. Each tablet should be taken as a whole (do not split) by mouth, with or without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only take this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Chlorpromazine?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Chlorpromazine or any other ingredients included in the manufacture of this medication.

Taking Chlorpromazine may cause drowsiness and alter your thoughts and movements. Avoid doing activities that require your full attention such as driving or operating machinery until you feel it is safe to do so. When getting up from a lying position, do it slowly and sit for a few minutes before standing up completely.

Taking Chlorpromazine may cause your skin to be more sensitive to sunlight. Avoid exposing yourself to excessive amounts of sunlight and wear protective clothing, sunscreen, and use sunglasses when going outdoors.

Inform your doctor if you will be handling insecticides, doing activities that are vigorous, or will be exposed to extreme heat.

Inform your doctor if you had any form of surgery or if you are planning to get one.

For the drug label information of Chlorpromazine, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Blurry vision
• Constipation
• Decreased sexual ability
• Drowsiness
• Dry mouth
• Insomnia
• Runny nose
• Urinary problems
• Weight gain

Serious side effects include:
• Confusion
• Difficulty breathing
• High fever
• Irregular heartbeats
• Lightheadedness
• Restlessness
• Seizure
• Sore throat
• Stiff muscles
• Tremors
• Uncontrolled facial movements
• Yellowing of the skin or eyes

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Chlorpromazine with any of the following medications:

• Alfentanil
• Atropine
• Bepridil
• Betapace
• Buprenorphine
• Celexa
• Cisapride
• Cordarone
• Corlanor
• Coumadin
• Disopyramide
• Droperidol
• Efavirenz
• Epipen
• Fentanyl
• Gatifloxacin
• Geodon
• Guanethidine
• Hydrocodone
• K-dur
• Lefamulin
• Lithium
• Meperidine
• Metoclopramide
• Morphine
• Nalbuphine
• Ozanimod
• Pentobarbital
• Phenobarbital
• Plaquenil
• Propoxyphene
• Quinidine
• Remifentanil
• Saquinavir
• Thioridazine
• Vandetanib

Ask your doctor or pharmacist for other possible interactions not listed within this section.

How should I store it?

Store Chlorpromazine in a tight container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Immediately call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Chlorpromazine in pregnant women has not established its developmental risks.

Data shows that Chlorpromazine is excreted in human milk and may cause harmful effects to the breastfed infant. Hence, the potential risks and benefits of using Chlorpromazine in pregnant or breastfeeding women should be carefully considered.

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