NOTE: Depending on the supplier/strength selected, the products shipped may have different packaging.

Why is Velphoro prescribed?

Velphoro is prescribed to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis. Elevated phosphorus levels are common in CKD and can lead to serious complications such as bone disorders and cardiovascular disease.

What does it do?

Velphoro is a phosphate binder that helps manage elevated phosphorus levels in the blood by binding dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream, and promoting its excretion through feces. Through this mechanism, Velphoro effectively reduces serum phosphorus and lowers the calcium-phosphorus product, contributing to better mineral balance.

How should I take it?

Always follow your doctor’s instructions, or the directions on the product label when taking this medication. Velphoro is typically prescribed at a dose of 500 mg three times a day, taken with meals. This dose may be adjusted based on an individual's serum phosphorus levels.

For optimal effectiveness, the tablets must be chewed or crushed and should not be swallowed whole. Taking Velphoro during meals enhances its phosphate-binding action, and the daily dose should be evenly distributed across meals to maintain consistent control of phosphorus levels.

What if I missed a dose?

If a dose of Velphoro is missed, it's important not to double up or try to make up for it by taking extra tablets. Instead, the medication should simply be resumed with the next scheduled meal.

What are the special precautions before taking Velphoro?

Inform your doctor about all the medications you are taking, your current and previous medical history. Before taking Velphoro, here are several important precautions to keep in mind:

Disclose all your current or past medical conditions to your doctor, particularly if you have:

• Intestinal surgery
• Hemochromatosis
• Liver problems
• Gastrointestinal disorders
• Peritonitis

Avoid sharing Velphoro with others even if their condition appears similar, as doing so may result in unexpected health risks or dangerous side effects.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects may include:
• Discolored (black) stool
• Diarrhea
• Nausea
• Tooth discoloration

Serious side effects may include:
• Difficulty breathing
• Gastrointestinal bleeding
• Rash or hypersensitivity reactions
• Sudden vision loss

This is not a complete list of potential side effects, and additional reactions may occur. For detailed information and medical guidance, consult your healthcare provider.

Is it safe to take it with another drug?

Velphoro (Sucroferric Oxyhydroxide) can interact with various medications, so it's important to check for potential interactions before taking it with another drug. Some interactions may increase side effects or reduce effectiveness.

Before taking Velphoro, consult your doctor if you are using any of the following medications:

• Doxycycline
• Aspirin
• Cephalexin
• Erdafitinib
• Levothyroxine

This is not a full list of possible drug interactions. To ensure your safety, it's essential to speak with your doctor or pharmacist before taking Velphoro alongside other medications, including over-the-counter drugs or supplements.

How should I store it?

Velphoro should be kept in its original container and stored at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

What action should I take in case of overdose?

In case of a Velphoro overdose, seek immediate medical attention even if no symptoms are present, as excessive intake may lead to gastrointestinal disturbances such as diarrhea, nausea, vomiting, abdominal pain, or constipation, and in rare cases, iron accumulation or bowel obstruction.

Is it safe for pregnant or breastfeeding women?

Velphoro is generally considered safe during breastfeeding because it is not systemically absorbed and is unlikely to pass into breast milk or affect the infant. However, its safety during pregnancy is not well established and should be guided by a healthcare provider’s assessment of potential risks and benefits.

If you're pregnant, considering pregnancy, or currently breastfeeding, it's important to speak with your healthcare provider to ensure that using this medication is safe for both you and your child.

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