Why is Vesanoid prescribed?

Tretinoin (Vesanoid) is prescribed for the treatment of acute promyelocytic leukemia in patients who have previously undergone chemotherapy but was not treated or whose condition improved but eventually became worse after chemotherapy.

What does it do?

Acute promyelocytic leukemia is a cancer of the bone marrow (the tissue in the bones responsible for producing blood cells). There is an accumulation of immature white and red blood cells and platelets causing symptoms such as bruising easily, nosebleeds, and red dots forming under the skin. Vesanoid belongs to a drug class called retinoids and it works by inhibiting the growth and spread of the cancerous cells by allowing the immature blood cells to develop normally.

How should I take it?

Vesanoid and its generic equivalents are currently available in 10mg capsules. Each capsule should be taken as a whole (do not split) by mouth, with food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, take it immediately and adjust the time of your next dose depending on your doctor’s advice. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Vesanoid?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Vesanoid or any other ingredients included in the manufacture of this medication.

Taking Vesanoid may cause severe headaches or dizziness. Avoid doing activities that require your full attention such as driving or operating machinery until you feel it is safe to do so.

Vesanoid may decrease the effectiveness of birth control pills. Consult your doctor for the best method of birth control while taking Vesanoid.

For the drug label information of Vesanoid, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Changes in vision
• Dry mouth
• Dry skin
• Fatigue
• Fever
• Hair loss
• Headache
• Nausea
• Rashes
• Vomiting

Serious side effects include:
• Balance problems
• Chest pain
• Coughing up blood
• Dark urine
• Lightheadedness
• Loss of appetite
• Ulcers in the mouth or throat
• Vision problems
• Yellowing of the skin or eyes

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Vesanoid with any of the following medications:

• Aminocaproic acid
• Aminolevulinic acid
• Aprotinin
• Arava
• Banzel
• Bexarotene
• Brigatinib
• Brigatinib
• Ceritinib
• Clofarabine
• Conivaptan
• Demeclocycline
• Diflucan
• Duvelisib
• Eravacycline
• Etravirine
• Etretinate
• Fosamprenavir
• Indinavir
• Isotretinoin
• Lomitapide
• Minocin
• Mipomersen
• Naltrexone
• Nizoral
• Omadacycline
• Oxytetracycline
• Pexidartinib
• Posaconazole
• Remdesivir
• Rheumatrex
• Saquinavir
• Sarecycline
• Soriatane
• Sporanox
• Teriflunomide
• Tetracycline
• Tranexamic acid
• Vfend
• Vibramycin
• Vilazodone
• Vitamin A
• Zytiga

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Vesanoid in its container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Present data suggest that the use of Vesanoid in pregnant women is contraindicated. It should not be taken when pregnancy is confirmed as it can cause harm to the fetus.

There is also limited data on the presence of Vesanoid in human milk or its effects on the breastfed infant.

The potential risks of taking Tretinoin outweigh the potential benefits and should not be taken by pregnant and breastfeeding women.

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