Why is Zytiga prescribed?

Abiraterone (Zytiga) is prescribed for the treatment of prostate cancer that has metastasized (spread to other parts of the body). It is used in combination with prednisone. It is prescribed when the cancer does not respond to alternative medications or surgery.

What does it do?

Prostate cancer is a type of cancer in males affecting the prostate (a gland that produces semen) and can cause signs and symptoms such as blood in semen, pelvic discomfort, and problems during urination. Zytiga belongs to a drug class called androgen biosynthesis inhibitors and it works by reducing the production of androgens (hormones that cause the tumor to grow).

How should I use it?

Zytiga and its generic equivalents are currently available in 250mg tablets. Each tablet should be taken as a whole (do not split) by mouth without food.

The dosage strength depends on every patient’s condition and the doctor’s prescription. It is imperative that you do not self-medicate and only use this drug after consulting with your doctor or pharmacist to determine the best dosage and dosing schedule for the treatment of your condition.

What if I missed a dose?

The desired effects of prescribed medications will only be achieved if taken properly. As much as possible, strictly follow your doctor’s prescribed dosing schedule. However, if you miss a dose, skip it and take it at your regular time on the following day. Never take two doses at the same time just to make up for your missed dose.

What are the special precautions before taking Zytiga?

Inform your doctor about all the medications you are taking, your current and previous medical history, and any allergic reactions to Zytiga or any other ingredients included in the manufacture of this medication.

Zytiga is only intended for men and should not be taken by women. Males with female partners should consult their doctor for effective birth control methods while taking Zytiga. It may also affect fertility in males.

For the drug label information of Zytiga, click here.

Does it have any side effects?

It is important to note that all drugs have corresponding side effects and adverse reactions. Additional information may be obtained when you ask your doctor or pharmacist.

Common side effects include:
• Bruising
• Constipation
• Diarrhea
• Indigestion
• Muscle pains
• Runny nose
• Sore throat
• Swollen or painful joints
• Vomiting

Serious side effects include:
• Confusion
• Fast heartbeats
• Headache
• Lightheadedness
• Muscle weakness
• Pain in the legs
• Painful urination
• Shortness of breath
• Swollen ankles or feet
• Yellowing of the skin or eyes

Is it safe to use it with another drug?

Some drug interactions may cause life-threatening reactions when taken with other medications. Immediately inform your doctor if you are taking Zytiga with any of the following medications:

• Amisulpride
• Anagrelide
• Apalutamide
• Bedaquiline
• Bepridil
• Betapace
• Brexpiprazole
• Ceritinib
• Cisapride
• Clozapine
• Cordarone
• Corlanor
• Crizotinib
• Disopyramide
• Dofetilide
• Dolasetron
• Edoxaban
• Eliglustat
• Enzalutamide
• Fingolimod
• Fosphenytoin
• Gatifloxacin
• Geodon
• Halofantrine
• Hydrocodone
• Lefamulin
• Lexapro
• Lomitapide
• Loperamide
• Mesoridazine
• Methadone
• Mifepristone
• Mitotane
• Nilotinib
• Ozanimod
• Phenobarbital
• Procainamide
• Quinidine
• Ribociclib
• Rifadin
• Tegretol
• Thioridazine
• Toremifene
• Vandetanib

If you are using any prescription, non-prescription, and herbal medications, inform your doctor and pharmacist for proper information and ask for other possible interactions not listed within this section.

How should I store it?

Store Zytiga in its container in a clean environment away from excessive heat and moisture.

What action should I take in case of overdose?

Call an ambulance and seek immediate medical attention to prevent further complications or possible death.

Is it safe for pregnant or breastfeeding women?

Zytiga is intended only for men and should not be taken by women.

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